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Characteristic API Advanced Intermediate Impurity

Carbamic acid, N-[(1S)-2-[(1R,3R,5R)-3-(aminocarbonyl)-2-azabicyclo[3.1.0]hex-2-yl]-1-(3-hydroxytricyclo[3.3.1.13,7]dec-1-yl)-2-oxoethyl]-, 1,1-dimethylethyl ester

CAS No.：1564266-87-0
Product No.：66-8A
Configuration：绝对构型
From：工艺杂质
Tricyclo[3.3.1.13,7]decane-1-acetic acid, α-[[(1R)-2-hydroxy-1-phenylethyl]amino]-, hydrochloride (1:1), (αS)-

CAS No.：361441-96-5
Product No.：65-4
Configuration：绝对构型
From：工艺杂质
Tricyclo[3.3.1.13,7]decane-1-acetonitrile, α-[[(1R)-2-hydroxy-1-phenylethyl]amino]-, (αS)-

CAS No.：361441-95-4
Product No.：65-3
Configuration：绝对构型
From：工艺杂质
Tricyclo[3.3.1.13,7]decane-1-carboxaldehyde

CAS No.：2094-74-8
Product No.：65-2
Configuration：无
From：工艺杂质
1-Adamantylmethanol

CAS No.： 770-71-8
Product No.：65-1
Configuration：无
From：工艺杂质
Tricyclo[3.3.1.13,7]decane-1-acetic acid, α-[[(1,1-dimethylethoxy)carbonyl]amino]-3-hydroxy-, (αR)-

CAS No.：1334321-39-9
Product No.：65-7A
Configuration：绝对构型
From：工艺杂质

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Characteristic API Advanced Intermediate Impurity

Carbamic acid, N-[(1S)-2-[(1R,3R,5R)-3-(aminocarbonyl)-2-azabicyclo[3.1.0]hex-2-yl]-1-(3-hydroxytricyclo[3.3.1.13,7]dec-1-yl)-2-oxoethyl]-, 1,1-dimethylethyl ester

Tricyclo[3.3.1.1<sup>3,7</sup>]decane-1-acetic acid, α-[[(1R)-2-hydroxy-1-phenylethyl]amino]-, hydrochloride (1:1), (αS)-

Tricyclo[3.3.1.1<sup>3,7</sup>]decane-1-acetonitrile, α-[[(1R)-2-hydroxy-1-phenylethyl]amino]-, (αS)-

Tricyclo[3.3.1.1<sup>3,7</sup>]decane-1-carboxaldehyde

1-Adamantylmethanol

Tricyclo[3.3.1.13,7]decane-1-acetic acid, α-[[(1,1-dimethylethoxy)carbonyl]amino]-3-hydroxy-, (αR)-

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Characteristic APIAdvanced IntermediateImpurity

Carbamic acid, N-​[(1S)​-​2-​[(1R,​3R,​5R)​-​3-​(aminocarbonyl)​-​2-​azabicyclo[3.1.0]​hex-​2-​yl]​-​1-​(3-​hydroxytricyclo[3.3.​1.13,​7]​dec-​1-​yl)​-​2-​oxoethyl]​-​, 1,​1-​dimethylethyl ester

Tricyclo[3.3.1.1<sup>3,​7</sup>]​decane-​1-​acetic acid, α-​[[(1R)​-​2-​hydroxy-​1-​phenylethyl]​amino]​-​, hydrochloride (1:1)​, (αS)​-

Tricyclo[3.3.1.1<sup>3,​7</sup>]​decane-​1-​acetonitrile, α-​[[(1R)​-​2-​hydroxy-​1-​phenylethyl]​amino]​-​, (αS)​-

Tricyclo[3.3.1.1<sup>3,​7</sup>]​decane-​1-​carboxaldehyde

1-Adamantylmethanol

Tricyclo[3.3.1.13,​7]​decane-​1-​acetic acid, α-​[[(1,​1-​dimethylethoxy)​carbonyl]​amino]​-​3-​hydroxy-​, (αR)​-

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Characteristic API Advanced Intermediate Impurity

Carbamic acid, N-[(1S)-2-[(1R,3R,5R)-3-(aminocarbonyl)-2-azabicyclo[3.1.0]hex-2-yl]-1-(3-hydroxytricyclo[3.3.1.13,7]dec-1-yl)-2-oxoethyl]-, 1,1-dimethylethyl ester

Tricyclo[3.3.1.1<sup>3,7</sup>]decane-1-acetic acid, α-[[(1R)-2-hydroxy-1-phenylethyl]amino]-, hydrochloride (1:1), (αS)-

Tricyclo[3.3.1.1<sup>3,7</sup>]decane-1-acetonitrile, α-[[(1R)-2-hydroxy-1-phenylethyl]amino]-, (αS)-

Tricyclo[3.3.1.1<sup>3,7</sup>]decane-1-carboxaldehyde

Tricyclo[3.3.1.13,7]decane-1-acetic acid, α-[[(1,1-dimethylethoxy)carbonyl]amino]-3-hydroxy-, (αR)-